Abstract: Pulse cyclophosphamide (PCP) is a well established method for the treatment of lupus nephritis. PCP seems to produce better results, and lesser side effects, than oral cytotoxic drugs. We present here, our experience with this method, in 51 patients. All patients had a WHO type IV histological lesion, on light microscopy. Proteinuria, hematuria, leucocyturia, casts, BUN, creatinine, and blood pressure were measured before starting PCP and after each one. The first ...