Abstract: It is difficult to define what exactly is intractable RA. Intractable RA may be defined as a patient. resistant to standard treatment. The difficult point is how to define the standard treatment. Shall we say intractable disease to a patient resistant to single DMARD and an NSAID? Or shall we say intractabIe disease to a patient resistant to a combination of DMARD with low dose steroid and associated NSAID who ...
Rheumatoid Arthritis: Management problems - Anticoagulation.
Abstract: Rheumatoid arthritis is a common disease occurring in 1% of the population. Therefore it is not unusual to see a rheumatoid arthritis patient who needs anticoagulation therapy for another reason than her or his RA. Anticoagulation therapy has no contra-indication for RA itself. However many drugs used in RA may interfere with anticoagulant drugs. The major problem arises from NSAIDs, particularly salicylate. These drugs have a synergistic effect on coumadin ...