Abstract: Introduction: Vascular involvement, as a hallmark of Behcet’s disease (BD), involves arteries and veins of all size and may be a poor prognostic sign. Like the other manifestations of the disease, its prevalence varies widely according to the reports from different parts of the world (7.7 to 60%). The difference may be due to ethic variation or environmental factors. The aim of this study is to find the characteristics of ...
Vasculitis in Ocular Lesions Of Behcet’s Disease, Impact on Outcome.
Abstract: Introduction: Ocular lesions are the leading cause of morbidity in Behcet’s disease (BD). Many factors contribute to the loss of vision in BD, as uveitis, retinal vasculitis, and their secondary complications such as cataract, hemorrhage, vessel necrosis, neovascularization, optic atrophy, etc. The purpose of this study was to determine the impact of retinal vasculitis on the evaluation of ocular Behcet’s (OB) and its outcome after an early or late treatment. Materials & ...
Polymyositis in Iran, analysis of 124 patients.
Abstract: AIM: The aim of this study was to assess the demography of Polymyositis in Iran. Methods: In the past 20 years, we had seen 124 patients in Rheumatology Research Center. All patients were classified by the American College of Rheumatology classification criteria. Ninety five items were checked for every patient. All patients were followed regularly and the data were updated at each visit. Results: Seventy one patients were female. The female to ...
SCLERODERMA IN IRAN, ANALYSIS OF 350 PATIENTS.
Abstract: Aim: The aim of this study was to determine the clinical and the laboratory features of scleroderma in Iranian patients. Methods: This is a prospective study done on 350 patients from 1975 to 1995. The diagnosis of scleroderma was based on the clinical and the skin biopsy. One hundred clinical and laboratory data were completed for every patients . Results: The mean age was 29.7 years with a standard deviation (SD) of ...
SLE IN IRAN, ANALYSIS OF 1310 CASES.
Abstract: Aim: The aim of this study was to assess the demography of SLE in Iran. Methods: In the past 20 years, each patient referred to the Lupus Unit had a computerized form with 266 items. All patients were followed regularly and the data were updated at each visit. Results: We have seen 1310 SLE patients with the following characteristics: The mean age was 24 years, females 89.5%, males 10.5 %, fever 58%, ...
Cyclosporine in the treatment of severe ocular lesions of Behcet’s disease.
Abstract: Introduction: there are several reports of good effects of Cyclosporine A (Cs A) in the treatment of Behcet's disease (BD). We studied the long term effect, of A Cs A in a prospective open clinical trial on posterior uveitis (PU) and retinal vasculitis (RV) of BD. Materials & Methods: Twenty three patients with PU and / or RV diagnose as BD (according to the Iran and to the Japan criteria) ...
Effects of Suppressive Therapy with Levothyroxine on Bone Density.
Abstract: Increased thyroid hormones level is associated with diminished bone density. It has been clarified that thyroid hormones by sirculating bone resorption lead to decrease in bone density. Thyroid hormone in many cases as in Non - Toxic Grotre & in supplement therapy in hypothyroidism is used as a drug & it is possible that suppressive therapy with T4 causes subclinical - hyperthyroidism. Studies done in west has shown different results ...
Outcome measurement of ocular lesions in Behcet’s disease.
Abstract: The outcome of ocular manifestations of Behcet’s Disease remains uncertain and unpredictable despite cytotxic drugs. One of our recent studies, presented to the 1995 Korean Rheumatology Annual Meeting, showed that one third of patients were None Responders, regardless of what treatment used. This study was designed to search for factors predicting the final outcome at the beginning of the treatment. Patients having more than one year of treatment were selected ...
Overview Of Pathogenesis & Management Of Behcet’s Disease.
Abstract: Genetic Background: Behcet’s Disease (BD) is known t0 be associated with the HLA-B5 gene. The association is with the B51subtype, the B*5101allele. The tryptophan amino acid in position 167 and histidine in position 171 seems to determine the susceptibility of B51 for BD. However all persons with B51 do not have BD and all BD patients do not have B51. Some particularity in the TNFβ gene region in BD patients ...
Proposed ocular Behcet therapeutic scoring & activity/chronicity ratio.
Abstract: Behcet’s Unite, Shariati Hospital the aim to propose a scoring system for the treatment of the ocular inflammation one vasculitis by our medications and to evaluate the state of the activity of the eye. Eleven activity and five chronicity (constant) parameters are scored from zero to four to consider the condition of each eye. The activity variables are: episcleritis &/or scleritis, anterior uveitis, hyalites, IMU, central periphlebitis &/or thrombosis, central periartertis, peripheral ...