Abstract: Antimalarials are among the most important disease modifying drugs used in Rheumatology. The major problem with them is their effects on eyes. We have done a retrospective study on 1598 patients with RA and SLE using Chloroquine for 1 month to 16 years (Mean 41 months). Eye problems was detected in 330 patients (20.6%). We found corneal deposition in 205 (13%) that was graded as severe (11%), moderate (12%) and ...
CHILBLAIN LUPUS ERYTHEMATOSUS IN A MONOLYGOTE TWIN.
Abstract: CHILBLAIN LUPUS ERYTHEMATOSUS IN A MONOLYGOTE TWIN.#C. Chams, M. Akbarian, P. Mansoori, F. Shahram, and F. Davatchi#Revista Espanola de Reumatologia, 1993; 20 (Suppl 1): p. 358 #Chilblain lupus erythematosus or lupus pernio was described by HUTCHINSON in 1888. Even actually it is difficult to put this entity in a well defined nosologic place as systemic lupus erythematosus. We report here the case of a twin monozygote brothers of 11 years old, ...
Audio vestibular involvement in Behcet's disease (BD).
Abstract: There is only three reports on the frequency of audio vestibular involvement in BD in the literature. In these studies, done in small population of BD patients, the frequency of auditory involvement were reported as high as 60%, and the vestibular involvement between 25 to 37%. We studied prospectively the audio vestibular involvement in 80 patients with BD, and compared them with 102 controls (CG) including hospital staffs, patients with ...
SYSTEMIC LUPUS ERYTHEMATOSUS AND INFECTION, ANALYSIS OF 893 SLE PATIENTS IN IRAN.
Abstract: An increased rate of infection among SLE patients has long been reported from western countries. In a retrospective study in 893 patients, we analyzed 203 cases who had one or more episodes of infection between 1974 and 1992. Among them 181 were females and 22 were males (89% female) . The diagnosis of infection was established by both clinical and laboratory findings. Almost more than half of the infections were ...
EVALUATION OF DIAGNOSTIC (`CLASSIFICATION') CRITERIA IN BEHCET'S DISEASE-TOWARDS INTERNATIONALLY AGREED CRITERIA. BY THE INTERNATIONAL STUDY GROUP FOR BEHCET'S DISEASE.
Abstract: No fewer than five sets of diagnostic criteria for Behcet's disease are currently in use. The International Study Group have therefore undertaken an extensive study of existing criteria and have developed recommended new international criteria based on the collection of data from 914 patients with Behcet's disease and 308 controls, of whom 886 (97%) and 97 respectively had mouth ulceration. It is recommended that these new criteria should replace the ...
Case report: Hypophosphatemic Osteomalacia in von Recklinghausen Neurofibromatosis.
Abstract: Skeletal lesions are not uncommon in von Recklinghausen neurofibromatosis, Most of them are considered to be dysplastic in nature. Association of osteomalacia or rickets with neurofibromatosis has been documented only rarely. Reported herein is a 40-year-old woman with known von Recklinghausen neurofibromatosis who presented with bone pain, multiple pseudofractures, marked increase in osteoid by bone biopsy, and hypophosphatemia with renal phosphate wasting. Treatment with oral phosphate and vitamin D ...
Pulse cyclophosphamide in Lupus Nephritis.
Abstract: The prognosis of Lupus Nephritis has dramatically changed since the introduction of cytotoxic drugs in their treatment. Different protocols have been proposed to reach this goal. Pulse cyclophosphamide (PCP) was first introduced in the treatment of Systemic Lupus Erythematosus by Sessoms & Kovarsky in 1984. Austin and Colleagues demonstrated it's superiority upon other regimens in Lupus Nephritis in 1986. Pulse Cyclophosphamide is now a well established method for the treatment ...
Behcet's Disease: review of 100 cases. Report of juvenile, Familial, and unilateral forms.
Abstract: In this case study 100 patients with confirmed Behcet's disease have been in reviewed. The following manifestations were observed: buccal aphthous ulcerations 98 per cent, genital ulcerations 63 per cent, positive Behcetine test in 81 per cent, ocular involvement 80 per cent, positive HLA-B5 74 per cent, skin lesions 68 per cent, articular manifestations 63 per cent, digestive problems 21 per cent, thrombophlabitis of the extremities 17 per cent, neurologic ...