Abstract: In systemic lupus eryThematosus (SLE) various antibodies are produced against cells including platelets and result in thrombocytopenia. !n the literature, the incidence of thrombocytopenia varied from 7% to 52%, in seven series of SLE patients with a mean cumulative percentage of 14.5% (1-5 ). SLE patients referred to the Lupus Unit of the Rheumatology Research Center. Tehran University for Medical Sciences. (Shariati Hospital) during the period of 1975 to 1977 ...
APLAR validation of Behcet’s disease (BD) diagnosis criteria, Iran experience.
Abstract: Considering that the majority of BD patients are from APLAR (Asia and Pacific League of Associations for Rheumatology) countries any diagnosis criteria for BD must have an adequate accuracy in these countries. The APLAR subcommittee for Behcet's Disease has set a prospective study to assess the accuracy of the existing diagnosis criteria. China, Iran, Japan, and Korea, the major countries with BD are participating to this study. The data from ...
Audiovestibular involvement in Behcet’s Disease (in patients with disease duration of more than 5 years).
Abstract: Introduction: We have previously shown that audio vestibular involvement is not frequent in early Behcet's disease (BD) at the time of diagnosis. This study was designed to clarify the frequency of audio vestibular involvement in patients with more chronic disease. Materials 8 Methods: We studied 60 BD patients with a disease duration of at least 5 years Patients were compared in a prospective study, to 28 controls (age and sex ...
Behcet’s disease treatment.
Abstract: There is not yet an effective treatment for all lesions of Behcet's disease and for all patients with Behcet's disease. The highest morbidity is from the ocular lesions. The mortality, although rare, is due to neurological and pulmonary involvement. Thrombosis of the large veins and arteries, also rare, may lead to morbidity and mortality. In daily practice, the best treatment for muco cutaneous lesions is colchicine. Thalidomide may be efficient ...
Proposed ocular Behcet therapeutic scoring and activity/chronicity ratio.
Abstract: The aim of this study is to propose a scoring system to determine the activity of the eyes, and to evaluate our medications in the treatment of ocular inflammation and vasculitis in Behect's disease (BD). Eleven activity and 5 chronicity (constant) parameters are scored from zero to 4 to consider the condition of each eye in Oculo-Behcet's disease. Both parameters are considered in our therapeutic scoring. The activity variables are: Episcleritis and/or ...
IN TIME VARIATION OF PATHERGY PHENOMENON IN BEHCET'S DISEASE.
Abstract: The pathergy phenomenon (PP) is one of the hallmarks of Behcet's Disease (BD). It has been reported to be positive from 17.5% to 83% of cases in different studies. PP is used as a diagnosis criterion in the Dilsen criteria, the Japan criteria, the International criteria, and the Iran criteria. It is therefore important to know wether PP is a fix manifestation of the disease or a cyclic manifestation ...
Long-Term Follow up of Type IV SLE Nephritis (without renal failure) Treated by Pulse Cyclophosphamide.
Abstract: Results of PCP are well known in lupus nephritis. We present here it’s outcome in patients with WHO type IV lupus nephritis, treated before the occurrence of renal failure. Patients having a follow up of more than 36 months were selected for this study. 29 patients fulfilled the selection criteria. Proteinuria, hematuria, leucocyturia, cast, BUN, creatinine and blood pressure were measured before PCP and after each one. The first and ...
SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) IN CHILDREN, ANALYSIS OF 220 IRANIAN CASES.
Abstract: Systemic Lupus Erythematosus is not rare in Iran. We have seen 220 cases in children in a population of 893 SLE in the past 16 years. In this study we show the features of SLE in children. The female to male ratio was 86/14. Fever was present in 72% of the patients, weight loss in 40%, malar rash in 72.5%, photosensitivity in 54%, mucosal lesion in 48%, discoid rash in ...
SALMONELLA INFECTION IN SYSTEMIC LUPUS ERYTHEMAT0SUS.
Abstract: Systemic Lupus Erythematosus (SLE) is a known underlying disease predisposing to salmonellosis. We report here 39 cases of salmonellosis in 30 patients in a population of 897 patients with SLE, during a 17 years period. All were women with a mean age of 25.7 years. Eighty percent were taking prednisolone and 26% cytotoxics at the onset of the infection. Renal involvement was present in 77% (type IV WHO in 65% ...
Prospective study on Neuro-Behcet.
Abstract: Behcet Disease (BD) is known to involve nervous system. In order to evaluate the prevalence of neurological complications as early manifestations of BD, and to determine their value as indicators of the disease, we conducted a prospective study on 261 consecutive patients reffered to our BD clinic (100 control subjects and 161 BD patients), including a Questionaire about neurological symptoms, complete physical (neruological) examination, and paraclinicalstudies, No definite (significant) difference ...