Abstract: Objectives: The aim of this study is to analyze the clinical features, laboratory findings and type of treatments in late onset SLE (after 50 years) in Iranian patients and compare them with the early onset. Methods: Records of 1419 SLE patients who attended our lupus unit, between 1975 and 1999 were reviewed. Nineteen Patients with late onset disease were identified. For comparison, 47 patients with disease onset before the age of ...
TREATMENT OF OCULAR MANIFESTATIONS OF BEHCET’S DISEASE.
Abstract: INTRODUCTION : Ocular manifestations are one of the main features of Behcet’s Disease. They occur in more than half the patients. In our series they were seen in 58% of cases1. The natural course of Ocular manifestations, like other manifestations of Behcet's Disease, is a progression by repetitive attacks followed by remission. However, on the contrary of other lesions (muco-cutaneous) the remission is much slower in posterior uveitis, and practically absent ...
MUCO CUTANEOUS LESIONS OF BEHCET'S DISEASE.
Abstract: Muco-cutaneous lesions are the most important signs in the diagnostic criteria of Behcet’s Disease (BD), but they are not specific and can be seen in other disease too. Mucous Membrane Lesions: 1- Recurrent oral aphthosis is the most frequent lesion of BD (96.1%0.6). It was divided in major, minor, and herpetiforme aphtosis. There are also Punctiform, Miliaria, and giant aphthosis. The shape and the size of aphthae can vary ...
ORIGIN AND OUTCOME OF MACULAR EDEMA IN OCULAR-BEHCET.
Abstract: The chronic macular edema, frequent in ocular Behcet's disease, is a treat to the visual outcome of the patients. We have investigated the origin, risk-factors and the outcome of macular edema in patents under immunosuppressors and corticosteroid therapy. This is a retrospective, case series study. In 1999,seventeen patients of the Behcet's clinic of Shariati hospital of Tehran who had macular edema were consecutively selected and included in the study. They were ...
The Impact of the Treatment Delay on the Outcome of Vision in Ocular Lesions of Behcet's Disease.
Abstract: Introduction: Ocular lesions of Behcet’s disease (BD) progress by recurrent attacks and remission. Their natural history, without treatment, is toward severe loss of vision or blindness. We presented last year a work to the ACR meeting on the long-term outcome of visual acuity (VA) in BD. The data showed that the final VA was related to the baseline VA (before the treatment), suggesting that a delay in aggressive treatment may ...
THE INFLUENCE OF PATHERGY TEST ON THE ACCURACY OF DIFFERENT DIAGNOSIS CRITERIA FOR BEHCET’S DISEASE.
Abstract: Introduction: Pathergy test (PAT) is used in the majority of diagnosis criteria set for Behcet’s Disease (BD). The modality of performing it (needle gauge, sharpness of the tip, direction of skin penetration, with or without a product injection), the delay to read the result (24 or 48 hours), and the cut-off line for positive test is not standardized. Therefore the results differ from one center to another, introducing a great ...
RHEUMATIC DISEASES IN A SINGLE FAMILY SET UP; "REPORT OF SIMILAR CASES IN FOUR FAMILIES".
Abstract: Background: The gene effect in pathogenesis of Rheumatic Diseases is well known, but the exact mode of transmission is not clear. In this report we present similar diseases occurred in two generations and in siblings. Methods: We overviewed the medical charts of second member of the family, according to the family history of the index patient. Results: Family I: Discoid Lupus was diagnosed in an eight years old girl whose father had ...
THE INFLUENCE OF SEX ON THE FREQUENCY OF CLINICAL SYMPTOMS IN BEHCET’S DISEASE.
Abstract: Introduction: It is known from long date that some manifestations are seen more frequently in men than women and in some of them the difference may be statistically significant. The aim of this study was to address that issue and to find if a statistical difference was of any clinical relevance or significance Materials and Methods: All patients of the BD registry (4717 at January 20, 2002) entered the ...
THE ORAL AND RADIOLOGICAL MANIFESTATIONS OF SYSTEMIC SCLEROSIS IN IRANIAN PATIENTS.
Abstract: Objective: Oral involvement is one of the most important manifestations in systemic sclerosis. We studied clinical and radiological presentations of patients with systemic sclerosis in IRAN. Methods: This study is a prospective case series on forty patients with systemic sclerosis (29 limited & 11 diffuse form) according to ACR (American College of Rheumatology) criteria, referred to Rheumatology Research Center from 2000-2001. For every patient, 41 data surveyed. Results: The mean age of ...
THE EFFECT OF COMBINED DRUG TREATMENT USING CHLOROQUINE AND METHOTREXATE ON THE STATUS OF ANTIOXIDANT CAPACITY OF PLASMA IN RHEUMATOID ARTHRITIS.
Abstract: Introduction: Oxygen free radicals that are generated mainly through the phagocytic activity of the polymorphonuclear leucocytea have been implicated as mediators of tissue damage in patients with rheumatoid arthritis (RA). Accordingly low levels of antioxidants, which increase free radical activity, are clearly associated with an increased risk of RA. Methods: Of 24 patients who entered the study 14 patients were excluded because they failed regular follow up. The analysis was ...