Abstract: Antimalarials are among the most important disease modifying drugs used in Rheumatology. The major problem with them is their effects on eyes. We have done a retrospective study on 1598 patients with RA and SLE using Chloroquine for 1 month to 16 years (Mean 41 months). Eye problems was detected in 330 patients (20.6%). We found corneal deposition in 205 (13%) that was graded as severe (11%), moderate (12%) and ...
Abstract: CHILBLAIN LUPUS ERYTHEMATOSUS IN A MONOLYGOTE TWIN.#C. Chams, M. Akbarian, P. Mansoori, F. Shahram, and F. Davatchi#Revista Espanola de Reumatologia, 1993; 20 (Suppl 1): p. 358 #Chilblain lupus erythematosus or lupus pernio was described by HUTCHINSON in 1888. Even actually it is difficult to put this entity in a well defined nosologic place as systemic lupus erythematosus. We report here the case of a twin monozygote brothers of 11 years old, ...
Abstract: Behcet's disease (BD) is not rare in children, and it's clinical picture differs from that in adults. We studied 66 patients in whom the disease was diagnosed under the age 16 from a population of 2068 BD patients. Comparison of the results with the adults by the student paired t test showed: although the most frequent initial manifestation of BD in children was oral aphthosis (54.5%), it was less frequent ...
Abstract: The annual incidence of Behcet's Disease (BD) is as high as 300 patients per year. The mean age at the onset of the first symptom is 26.7 years (SD = 9.7). The sex distribution is 54% male and 46% female. The initial manifestation was mainly oral aphthosis (73%), uveitis (13%), genital ulcerations (11%), arthritis (9%), and skin manifestations (9%). Clinical manifestations were as fallow: mucous membrane manifestations were seen in 95.5% ...
Abstract: There is only three reports on the frequency of audio vestibular involvement in BD in the literature. In these studies, done in small population of BD patients, the frequency of auditory involvement were reported as high as 60%, and the vestibular involvement between 25 to 37%. We studied prospectively the audio vestibular involvement in 80 patients with BD, and compared them with 102 controls (CG) including hospital staffs, patients with ...
Abstract: An increased rate of infection among SLE patients has long been reported from western countries. In a retrospective study in 893 patients, we analyzed 203 cases who had one or more episodes of infection between 1974 and 1992. Among them 181 were females and 22 were males (89% female) . The diagnosis of infection was established by both clinical and laboratory findings. Almost more than half of the infections were ...