Abstract: INTRODUCTION: The pathergy phenomenon (PP) is one of the hallmarks of Behcet's Disease (BD). It has been reported to be positive from 17.5% to 83% of cases in different studies. PP is used as a diagnosis criterion in the Dilsen criteria, the Japan criteria, the International criteria, and the Iran criteria. It is therefore important to know whether PP is a fix manifestation of the disease or a cyclic manifestation ...
Prolactin Level in Behcet’s Disease.
Abstract: Introduction: Prolactin (PRL) is an immune stimulating hormone and may be important in the pathogenesis of some autoimmune diseases, such as SLE. This study was designed to detect the PRL level in patients with Behcet's disease (BD), and its relation to the different manifestations of the disease. Materials & Methods: Thirty-seven new male patients with BD and 29 age matched control normal individuals (CON) was selected as every consecutive patient. The ...
Proposed ocular Behcet therapeutic scoring & activity/chronicity ratio.
Abstract: Behcet’s Unite, Shariati Hospital the aim to propose a scoring system for the treatment of the ocular inflammation one vasculitis by our medications and to evaluate the state of the activity of the eye. Eleven activity and five chronicity (constant) parameters are scored from zero to four to consider the condition of each eye. The activity variables are: episcleritis &/or scleritis, anterior uveitis, hyalites, IMU, central periphlebitis &/or thrombosis, central periartertis, peripheral ...
Treatment of Ophthalmologic Manifestations Of Behcet’s Disease Comparison Of 6 Methods.
Abstract: Introduction: Opthalmologic manifestations are the major cause of morbidity in Behcet’s Disease. If not treated, they usually progress toward sever loss of vision or blindness. Cytotoxic drugs are the main therapeutic agents. Materials & Methods: In an open, non randomized, control study, pulse cyclophosphamide (PCP), low dose pulse cyclophosphamide (LDP), weakly methtrexate (MTX), chlorambucil (CHL), oral cyclophosphamide (OCP), and cyclosporine A (CYA) were used in a standard protocol for 778 patients. ...
THE PREVALENCE OF CONVULSION, IT'S RELATION TO ANTI-DNA ANTIBODIES LEVELS AND MORTALITY OF PATIENTS WITH SYSTEMIC LUPUS ERYTHMATOSUS (SLE).
Abstract: Neuropsychiatric manifestations of SLE are frequent and usually serious, convulsion is one of the most important and hazardous symptoms of CNS-LUPUS. Because there are many differences in clinical manifestations frequency and severity of organ systems involvement, and cause of death in patients with SLE (in Iran and other countries) an analytic retrospective case-control study was carried out to evaluate the frequency of convulsion in relation with age and sex distribution, ...
PREVALENCE AND CLINICAL ASSOCIATION OF ANTICARDIOLIPIN ANTIBODIES IN SYSTEMIC LUPUS AND NON LUPUS DISEASE.
Abstract: Anti-cardiolipin antibodies (ACA) occur in patients with SLE, lupus-like illness and with some other illnesses, such as malignancy, syphilis and among healthy elderly. We found that the prevalence of IgG and IgM ACA isotopes in 147 Iranian SLE patients was 49.7% for IgG and 5.6% for IgM. In addition, some SLE and non-SLE patients from other centers were studied: the prevalence of ACA-IgG in SLE patients from Mashad was 54%; ...
Behcet’s Disease. Analysis of 2806 cases.
Abstract: There are only two nationwide surveys of Behcet's Disease (BD) in the world, one from Japan and one from Iran. The comparison of the two surveys is interesting because the populations are racially different, although they share same genetic background via the invasion of Iran by Turk tribes (from the northem part of China) in the 10 th and 13 th century. The annual incidence of BD in Iran is 350 ...
Study of Bone Mineral Density (BMD) in 1335 patients with non inflammatory diseases.
Abstract: In order to study a possible relation between mechanical bone pains and the BMD, 1335 patients were analyzed as every consecutive patient. The BMD was measured in a cohort study on 5927 patients referred for various reasons to the Rheumatology Research Center, Osteoporosis Unit. The BMD was measured by Dual Energy X-rays Absorptiometry (DEXA) on the lumbar spine (L1-L4) and the femoral neck. Patients having an inflammatory disease such as ...
Effects of the age of Menopause on Bone Mineral Density (BMD) in 716 Iranian Women.
Abstract: Menopause is one of the most important accelerating factors of bone loss in women. This study was designed to evaluate the effects of the age of menopause on BMD in Iranian women. The women referred for Bone Densitometry who were menopaused and did not have hysterectomy before their menopause were selected as every consecutive patient. Those who had any other risk factor for osteoporosis were excluded. The patients were divided ...
CD5-POSITIVE B CELLS In Rheumatoid Arthritis Patients.
Abstract: The concept that rheumatoid arthritis (RA) is an autoimmune disease is supported by variety of autoantibodies in patient's serum. The most important of these are rheumatoid factors (RFs), antibodies that react with the patient's own Ig. It has been suggested that IgM-RF plays a role in disease pathogenesis. The main source of IgM-RF are B cells that express the pan T-cell marker, CDS: We conducted this study to test the ...