Abstract: Introduction: We have previously shown that audio vestibular involvement is not frequent in early Behcet's disease (BD) at the time of diagnosis. This study was designed to clarify the frequency of audio vestibular involvement in patients with more chronic disease. Materials 8 Methods: We studied 60 BD patients with a disease duration of at least 5 years Patients were compared in a prospective study, to 28 controls (age and sex ...
Behcet’s disease and pregnancy.
Abstract: Introduction: Behcet's disease (BD) is a multisystem disorder with potential ability to influence pregnancy outcome. Changes in the BD may also occur during pregnancy. This study was designed to find the effect of pregnancy on BD and the outcome of pregnancy. Materials & Methods: We analyzed 59 pregnancies in 54 women with BD. The disease activity during pregnancy and in the 6 month period both before pregnancy and after delivery were ...
Outcome analysis of ocular lesions in Behcet’s disease with six different therapeutic methods.
Abstract: Introduction: Ocular lesions are the major cause of morbidity in Behcet's Disease. If not treated, they usually progress toward severe loss of vision or blindness. Cytotoxic drugs are the main therapeutic arsenal used for this condition. Materials & Methods: in an open, non randomized control study. Pulse Cyclophosphamida (PCP), low dose pulse cyclophosphamide (LDP), oral cyclophosphamide (OCP). weakly methotrexate (MTX), chlorambucil (CHL), and cyclosporine A (CYA) were used in a standard ...
Proposed ocular Behcet therapeutic scoring and activity/chronicity ratio.
Abstract: The aim of this study is to propose a scoring system to determine the activity of the eyes, and to evaluate our medications in the treatment of ocular inflammation and vasculitis in Behect's disease (BD). Eleven activity and 5 chronicity (constant) parameters are scored from zero to 4 to consider the condition of each eye in Oculo-Behcet's disease. Both parameters are considered in our therapeutic scoring. The activity variables are: Episcleritis and/or ...
Cyclosporine in severe Ocular Lesions of Behcet’s Disease.
Abstract: Introduction: There are several reports of good effects of Cyclosporine A (CsA) in the treatment of Behcet's disease (BD). We studied the long term effect of CsA in prospective open clinical trial on posterior uveitis (PU) and retinal vasculitis (RV) of BD. Materials & Methods: Twenty three patients with PU and/or RV diagnosed as BD (according to the Iran and to the Japan criteria) were selected. Initially CsA 5 mg/Kg/day orally ...
Cyclosporine in the treatment of severe ocular lesions of Behcet’s disease.
Abstract: Introduction: there are several reports of good effects of Cyclosporine A (Cs A) in the treatment of Behcet's disease (BD). We studied the long term effect, of A Cs A in a prospective open clinical trial on posterior uveitis (PU) and retinal vasculitis (RV) of BD. Materials & Methods: Twenty three patients with PU and / or RV diagnose as BD (according to the Iran and to the Japan criteria) ...
The Accuracy of IBDDAM in the Treatment Evaluation of Behcet’s Disease.
Abstract: Introduction: Behcet's disease (BD) is characterized by recurrent attacks followed by remissions, making difficult the assessment of a given treatment. The aim of this study was to compare the Iran Behcet's Disease Dynamic Activity Measure (IBDDAM) with the physician's global assessment (PGA) in evaluating the treatment result. Materials & Methods: Ninety-six patients with BD were followed prospectively, regardless of their treatment modality. The range of follow up was 3 to 62 ...
Iran’s Aspect of Behcet’s Disease in Children, the 1996 Survey.
Abstract: Introduction: There is considerable controversy in the characteristics of Behect's disease (BD) in children. The aim of this study is to show Iran's view m juvenile BD. Materials & Methods: Different manifestations of the disease were determined in the BD patients under the age of 16. They were compared with the adult patients by chi square test. Results: We had 102 children with BD. The male/female ratio was 1.04. Oral aphthosis (64%) ...
Outcome measurement of ocular lesions in Behcet’s disease.
Abstract: The outcome of ocular manifestations of Behcet’s Disease remains uncertain and unpredictable despite cytotxic drugs. One of our recent studies, presented to the 1995 Korean Rheumatology Annual Meeting, showed that one third of patients were None Responders, regardless of what treatment used. This study was designed to search for factors predicting the final outcome at the beginning of the treatment. Patients having more than one year of treatment were selected ...
IN TIME VARIATION OF PATHERGY PHENOMENON IN BEHCET'S DISEASE.
Abstract: The pathergy phenomenon (PP) is one of the hallmarks of Behcet's Disease (BD). It has been reported to be positive from 17.5% to 83% of cases in different studies. PP is used as a diagnosis criterion in the Dilsen criteria, the Japan criteria, the International criteria, and the Iran criteria. It is therefore important to know wether PP is a fix manifestation of the disease or a cyclic manifestation ...