Abstract: In Rheumatoid Arthritis (RA) osteoporosis is secondary. Its cause and its treatment are still controversial. All agents used in post menopausal osteoporosis have been tried for RA osteoporosis. Our work is a prospective open study to demonstrate the efficacy of low dose NF (20 mg daily) in these patients. Sixty two patients with RA and osteoporosis (t score less than 2.5 standard deviation, as defined by WHO) entered the study. BMD ...
Treatment of Osteoporosis by Natrium Fluoride.
Abstract: Natrium Fluoride (NF) is one of the best treatments of osteoporosis because it is cheap, it has no major side effects, and it is effective (Heany et al., Farley et al., Dure-Smith et al., Kanis et al., and Pak et al.). Our work is a prospective open study to demonstrate the efficacy of low dose NF (20 mg daily) in post menopausal osteoporosis. Fifty six patients with osteoporosis (t score less ...
Evaluation and Risk Factors in the Ocular Behcet’s Disease.
Abstract: Porpose: To determine the risk factors in the prognosis and the visual outcome of the disease. Methods: This is a retrospective study of 361 patients, having Behcet’s disease and treated by immunosuppressives and steroids, followed-up at Shariatti Hospital (mean duration of follow-up was 2.27 years). The ocular examinations at the first and last visit are recorded and compared. Results: Vision ...
SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) IN CHILDREN, ANALYSIS OF 220 IRANIAN CASES.
Abstract: Systemic Lupus Erythematosus is not rare in Iran. We have seen 220 cases in children in a population of 893 SLE in the past 16 years. In this study we show the features of SLE in children. The female to male ratio was 86/14. Fever was present in 72% of the patients, weight loss in 40%, malar rash in 72.5%, photosensitivity in 54%, mucosal lesion in 48%, discoid rash in ...
SALMONELLA INFECTION IN SYSTEMIC LUPUS ERYTHEMAT0SUS.
Abstract: Systemic Lupus Erythematosus (SLE) is a known underlying disease predisposing to salmonellosis. We report here 39 cases of salmonellosis in 30 patients in a population of 897 patients with SLE, during a 17 years period. All were women with a mean age of 25.7 years. Eighty percent were taking prednisolone and 26% cytotoxics at the onset of the infection. Renal involvement was present in 77% (type IV WHO in 65% ...
Relationship of pathergy phenomenon and Behcet's disease (BD) manifestations.
Abstract: In a study on 391 cases of BD presented to the EULAR Congress in 1987 we demonstrated that the following symptoms were seen more frequently in patients with positive pathergy phenomenon: oral aphthosis as the initial manifestation of the disease, genital ulcerations, pseudofolliculitis, and arthralgia. The following symptoms, on the contrary were seen less frequently: oral aphthosis, ankylosing spondylitis. It was interesting to look after those findings, 6 years later, in ...
Prospective study on Neuro-Behcet.
Abstract: Behcet Disease (BD) is known to involve nervous system. In order to evaluate the prevalence of neurological complications as early manifestations of BD, and to determine their value as indicators of the disease, we conducted a prospective study on 261 consecutive patients reffered to our BD clinic (100 control subjects and 161 BD patients), including a Questionaire about neurological symptoms, complete physical (neruological) examination, and paraclinicalstudies, No definite (significant) difference ...
Low dose pulse cyclophosphamide (LDP) in ophthalmological lesions of Behget's disease.
Abstract: Pulse cyclophosphamide (PCP) is the most effective and the least toxic treatment in posterior uveitis (pU) and/or retinal vasculitis (RV) of Behcet's disease (BD). Conventional doses (1 g/m2) may be associated with minor side effects such as hair loss, nausea and vomiting. To find whether lower doses, such as those already employed in Lupus nephritis should be useful, we administered IVLDP (0.5 g/m2/month) plus prednisolone (0.5 mg/kg/day) to 40 BD ...
Accuracy of existing diagnosis criteria for Behcet's disease (BD).
Abstract: There are 5 major sets of diagnosis criteria for BD: Mason & Barnes, O'Duffy, Dilsen, Japan revised criteria, and the International criteria (the latest one). To evaluate their accuracy we analysed their sensitivity and specificity in 2069 BD and 1519 control patients. The accuracy was calculated by the sum of BD patients fulfilling the criteria and the control patients correctly classified as non BD, divided by the sum of the ...
A SURVEY OF ANTIBODIES FOR THE EXTRACTABLE NUCLEAR ANTIGENS AND THEIR ROLE IN THE CLINICAL DIAGNOSIS AND PROGNOSIS OF SLE.
Abstract: Fifty-seven patients suffering from systemic lupus erythematosus with different clinical features were studied from various aspects of immunological abnormalities, including anti-nuclear antibodies; anti-DNA; anti-Sm (Smith's antigen); and, other extractable nuclear antigens. The tests employed were microhemagglutination, counter immunoelecterphoresis, and radio immunoassay (RIA). The comparison between the two techniques for detectiong anti-DNA titers showed a significant correlation between them. There was also a significant positive correlation between the presence of anti-DNA and lupus nephritis ...