Abstract: Introduction: There are several reports of good effects of Cyclosporine A (CsA) in the treatment of Behcet's disease (BD). We studied the long term effect of CsA in prospective open clinical trial on posterior uveitis (PU) and retinal vasculitis (RV) of BD. Materials & Methods: Twenty three patients with PU and/or RV diagnosed as BD (according to the Iran and to the Japan criteria) were selected. Initially CsA 5 mg/Kg/day orally ...
Cyclosporine in the treatment of severe ocular lesions of Behcet’s disease.
Abstract: Introduction: there are several reports of good effects of Cyclosporine A (Cs A) in the treatment of Behcet's disease (BD). We studied the long term effect, of A Cs A in a prospective open clinical trial on posterior uveitis (PU) and retinal vasculitis (RV) of BD. Materials & Methods: Twenty three patients with PU and / or RV diagnose as BD (according to the Iran and to the Japan criteria) ...
The Accuracy of IBDDAM in the Treatment Evaluation of Behcet’s Disease.
Abstract: Introduction: Behcet's disease (BD) is characterized by recurrent attacks followed by remissions, making difficult the assessment of a given treatment. The aim of this study was to compare the Iran Behcet's Disease Dynamic Activity Measure (IBDDAM) with the physician's global assessment (PGA) in evaluating the treatment result. Materials & Methods: Ninety-six patients with BD were followed prospectively, regardless of their treatment modality. The range of follow up was 3 to 62 ...
Iran’s Aspect of Behcet’s Disease in Children, the 1996 Survey.
Abstract: Introduction: There is considerable controversy in the characteristics of Behect's disease (BD) in children. The aim of this study is to show Iran's view m juvenile BD. Materials & Methods: Different manifestations of the disease were determined in the BD patients under the age of 16. They were compared with the adult patients by chi square test. Results: We had 102 children with BD. The male/female ratio was 1.04. Oral aphthosis (64%) ...
Prolactin Level in Behcet’s Disease.
Abstract: Introduction: Prolactin (PRL) is an immune stimulating hormone and may be important in the pathogenesis of some autoimmune diseases, such as SLE. This study was designed to detect the PRL level in patients with Behcet's disease (BD), and its relation to the different manifestations of the disease. Materials & Methods: Thirty-seven new male patients with BD and 29 age matched control normal individuals (CON) was selected as every consecutive patient. The ...
Proposed ocular Behcet therapeutic scoring & activity/chronicity ratio.
Abstract: Behcet’s Unite, Shariati Hospital the aim to propose a scoring system for the treatment of the ocular inflammation one vasculitis by our medications and to evaluate the state of the activity of the eye. Eleven activity and five chronicity (constant) parameters are scored from zero to four to consider the condition of each eye. The activity variables are: episcleritis &/or scleritis, anterior uveitis, hyalites, IMU, central periphlebitis &/or thrombosis, central periartertis, peripheral ...
THE PREVALENCE OF CONVULSION, IT'S RELATION TO ANTI-DNA ANTIBODIES LEVELS AND MORTALITY OF PATIENTS WITH SYSTEMIC LUPUS ERYTHMATOSUS (SLE).
Abstract: Neuropsychiatric manifestations of SLE are frequent and usually serious, convulsion is one of the most important and hazardous symptoms of CNS-LUPUS. Because there are many differences in clinical manifestations frequency and severity of organ systems involvement, and cause of death in patients with SLE (in Iran and other countries) an analytic retrospective case-control study was carried out to evaluate the frequency of convulsion in relation with age and sex distribution, ...
Bone mass density (BMD) in normal Iranian population.
Abstract: Introduction: BMD varies in different countries due to different genetic and environmental factors, It is necessary to determine BMD in normal population of Iran. This study was designed by the Rheumatology Research Center to fulfill this task. It was achieved by a grant from the Deputy Ministry for Research, the Ministry of Health, Treatment and Medical Education. Materials and methods: 280 normal Iranians were selected randomly from staffs of Shariati Hospital ...
Effects of the age of Menopause on Bone Mineral Density (BMD) in 716 Iranian Women.
Abstract: Menopause is one of the most important accelerating factors of bone loss in women. This study was designed to evaluate the effects of the age of menopause on BMD in Iranian women. The women referred for Bone Densitometry who were menopaused and did not have hysterectomy before their menopause were selected as every consecutive patient. Those who had any other risk factor for osteoporosis were excluded. The patients were divided ...
SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) IN CHILDREN, ANALYSIS OF 220 IRANIAN CASES.
Abstract: Systemic Lupus Erythematosus is not rare in Iran. We have seen 220 cases in children in a population of 893 SLE in the past 16 years. In this study we show the features of SLE in children. The female to male ratio was 86/14. Fever was present in 72% of the patients, weight loss in 40%, malar rash in 72.5%, photosensitivity in 54%, mucosal lesion in 48%, discoid rash in ...