Abstract: Introduction: The latest nationwide survey on Behcet’s disease (BD) in Iran was carried out in 2001. We present here its data, and compare it with the previous two surveys in 1991 (on 1882 patients) and 1996 (on 3153 patients). Patients & methods: The data of patients in the BD registry before the end of the year 2001 were collected on a standard protocol comprising 100 clinical and paraclinical items. A ...
ASSOCIATION OF HLA-B51 WITH CLINICAL EXPRESSION OF BEHCET’S DISEASE, ANALYSIS OF 201 IRANIAN PATIENTS.
Abstract: Introduction: Despite the strong association between HLA-B51 and Behcet’s disease (BD), the clinical significance of this genetic marker has not been fully elucidated. The aim of this study was to find out the association of HLA-B51 with various manifestations of BD, and to compare it to those of HLA-B5. Patients & methods: All newly diagnosed BD patients in a 9-month period from April 2001 to January 2002 were studied. They ...
HLA-B51 FREQUENCY IN IRANIAN PATIENTS WITH BEHCET’S DISEASE.
Abstract: Introduction: HLA-B51, a split antigen of HLA-B5, has generally been associated with Behcet’s disease (BD) in different countries notably those along the Silk route. The aim of this study was to determine the frequency of HLA-B51 in Iranian patients with BD, and to compare it with the control patients. Patients & methods: In a prospective study, 599 consecutive new patients referred to the BD clinic, in a 9-month period from ...
CHRONOLOGY OF CLINICAL MANIFESTATIONS IN BEHCET’S DISEASE, ANALYSIS OF 3542 CASES.
Abstract: Introduction: Manifestations of Behcet’s disease (BD) appear one after another during the course of the disease. Some involvements such as mucous lesions seem to appear early, and others such as gastrointestinal (GI) and neurological (CNS) involvement many years later. This study was planned to find out the chronology of different manifestations of BD. Patients & methods: In a retrospective study, files of all BD patients diagnosed since 1989 were reviewed ...
AZATHIOPRINE AND LOW DOSE PULSE CYCLOPHOSPHAMIDE IN SEVERE OCULAR LESIONS OF BEHCET’S DISEASE, A PRELIMINARY REPORT.
Abstract: Introduction: Combination of cytotoxic drugs was suggested to decrease the rate of non-responders in severe ocular lesions of Behcet’s disease (BD). We present here our preliminary data with low dose pulse Cyclophosphamide (LDP) and Azathioprine (AZA) in the treatment of posterior uveitis (PU) and/or retinal vasculitis (RV) of BD. Patients & methods: Twelve BD patients with PU and RV were selected. They all received LDP as 0.5 g/m2 body surface/month ...
TONSILLECTOMY AND BEHCET’S DISEASE.
Abstract: Introduction: Increasing development of some diseases such as Behcet’s disease (BD) was reported after tonsillectomy. This study was designed to find the association between tonsillectomy/adenoidectomy (T/A) and subsequent development of BD. Patients & methods: In a prospective control study, 128 patients with BD and 139 controls from the orthopedic clinic (age and sex matched) were studied regarding previous T/A. A complete ENT clinical examination was performed for all of them. ...
URINE ABNORMALITIES IN BEHCET’S DISEASE, STUDY OF 4704 CASES.
Abstract: Introduction: Despite the multisystem nature of Behcet’s disease (BD), renal involvement is rare in this disease. The aim of this study was to find the prevalence and characteristics of urine abnormalities and renal involvement of BD in Iran. Patients & methods: In a cohort of 4704 patients with BD, urinalysis was performed to screen patients with urine abnormalities. Different manifestations of the disease, including 100 clinical and paraclinical parameters, were ...
EVALUATION OF THE MORTALITY IN SLE, ANALYSIS OF 165 PATIENTS.
Abstract: Objective: SLE is an autoimmune disease. The mortality rate and causes are different in the various countries. The present study is done to find out the causes of mortality in the SLE patients in Iran. Methods: This study was retrospective according to medical records of patients who were referred to Rheumatology polyclinic, admitted in Rheumatology ward, ICU, Gynecology and Nephrology wards of Shariati hospital during 10 years, from 1991-2001. Results: Of 2021 ...
JOINT HYPER-MOBILITY (JHM) IN IRANIAN STUDENTS.
Abstract: Objectives: Joint Hyper-Mobility is an important and occult joint involvement in normal population. We studied to determine the prevalence and features of JHM in Iranian students. Methods: A group of Iranian primary to high school students in Tehran was considered in the figure of a cross sectional-descriptive study. Though validated Carter-Wilkinson & Beighton criteria 997 students from five geographical regions were screened. Sampling method was Randomized - multi process. We had ...
LATE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS IN IRAN.
Abstract: Objectives: The aim of this study is to analyze the clinical features, laboratory findings and type of treatments in late onset SLE (after 50 years) in Iranian patients and compare them with the early onset. Methods: Records of 1419 SLE patients who attended our lupus unit, between 1975 and 1999 were reviewed. Nineteen Patients with late onset disease were identified. For comparison, 47 patients with disease onset before the age of ...