Abstract: INTRODUCTION: Behcet’s Disease (BD) is classified among vasculitides, but its clinical picture is very distinctive and can be easily differentiated from the others. BD was originally seen along the Silk Road, but due to immigrations it is now seen everywhere in the world. There are many reports on clinical manifestations of BD from different parts of the world. The majority are case series except two nationwide surveys, one from Iran1, ...
JOINT HYPER-MOBILITY (JHM) IN IRANIAN STUDENTS.
Abstract: Objectives: Joint Hyper-Mobility is an important and occult joint involvement in normal population. We studied to determine the prevalence and features of JHM in Iranian students. Methods: A group of Iranian primary to high school students in Tehran was considered in the figure of a cross sectional-descriptive study. Though validated Carter-Wilkinson & Beighton criteria 997 students from five geographical regions were screened. Sampling method was Randomized - multi process. We had ...
THE ORAL AND RADIOLOGICAL MANIFESTATIONS OF SYSTEMIC SCLEROSIS IN IRANIAN PATIENTS.
Abstract: Objective: Oral involvement is one of the most important manifestations in systemic sclerosis. We studied clinical and radiological presentations of patients with systemic sclerosis in IRAN. Methods: This study is a prospective case series on forty patients with systemic sclerosis (29 limited & 11 diffuse form) according to ACR (American College of Rheumatology) criteria, referred to Rheumatology Research Center from 2000-2001. For every patient, 41 data surveyed. Results: The mean age of ...
Immunopathogenesis Of Behcet's Disease.
Abstract: Objectives: The etiology and pathogenesis of Behcet's disease (BD) are still unknown. It seems that in a special genetic background exogenous or endogenous antigen(s) acts as trigger in up regulating and presenting the pathogenic epitope. The immune system reacts in an abnormal way, by inducing a cascade of cytokines and chemokines to stimulate innate immune responses, leading to the lesions of the disease. Genetic background: The major susceptibility gene is the ...
PREGNANCY OUTCOME IN SYSTEMIC LUPUS ERYTHEMATOSUS.
Abstract: Objective: To assess the course of maternal disease and outcome of pregnancy in patients with systemic lupus erythematosus (SLE). Patients and Methods: One hundred SLE patients who carried out 128 pregnancies were studied retrospectively. These patients were followed in lupus unit every one to two months by the rheumatologist and obstetrician team throughout pregnancy. Some patients were given prophylactic low-dose Prednisolone. Lupus flares were treated by increasing Prednisolone doses. Patients who ...
THE PREVALENCE OF CONVULSION, IT'S RELATION TO ANTI-DNA ANTIBODIES LEVELS AND MORTALITY OF PATIENTS WITH SYSTEMIC LUPUS ERYTHMATOSUS (SLE).
Abstract: Neuropsychiatric manifestations of SLE are frequent and usually serious, convulsion is one of the most important and hazardous symptoms of CNS-LUPUS. Because there are many differences in clinical manifestations frequency and severity of organ systems involvement, and cause of death in patients with SLE (in Iran and other countries) an analytic retrospective case-control study was carried out to evaluate the frequency of convulsion in relation with age and sex distribution, ...
Long-term follow-up of pulse cyclophosphamide (PCP) in ocular Behcet.
Abstract: PCP was administered as 1 g cyclophosphsmide/m2/body surface, once per month, with 0.5mg prednisolone/kg/day, to 71 patients with severe posterior uveitis (PU) and/or retinal vasculitis (RV) , A Disease Activity Index (DAI) was calculated for each section of each eye, before the first PCP and then after each one. When a remission was obtained the gap between, PCP was increased gradually and prednisolone was tapered. If the result remained ...