Abstract: Pattern of Rheumatic Diseases in Iran: They have the same frequency and the same pattern as in Western countries. A study from 1993 demonstrated a prevalence of 32.6% among adults (31.4% in the USA, Cunningham 1984). Inflammatory disorders counted for 11% of all rheumatic diseases. The ratio of RA to AS was 8/1 (7/1 in USA), and SLE to Scleroderma 3.5/1 (3.6/1 in USA). Psoriatic arthritis and Reiter's syndrome were ...
LONG-TERM OUTCOME OF VISION IN BEHCET'S DISEASE.
Abstract: INTRODUCTION: The natural history of ocular lesions in Behcet's Disease (BD) is gradual progressions of lesions toward severe loss of vision or blindness. The association of cytotoxic drugs and steroids has dramatically changed the outcome. However, some authors still believe that the improvement is temporary and in the long run (10 years) the eyes progress toward blindness no matter what treatment was applied. The aim of this study was to ...
LONG-TERM OUTCOME OF VISION IN BEHCET’S DISEASE.
Abstract: INTRODUCTION: The natural history of ocular lesions Behcet’s Disease (BD) is gradual progressions of lesions toward severe loss of vision or blindness. The association of cytotoxic drugs and steroids has dramatically changed the outcome. However, some authors still believe that the improvement is temporary and in the long run (10 years) the eyes progress toward blindness no matter what treatment was applied. The aim of this study was to address ...
Is acne vulgaris seen more often in Behcet Disease than in the normal population?
Abstract: Background: In the literature, some of the skin pustular lesions of BD resembling the pustular lesion of acne vulgaris (AV) was called acneiform lesion of BD. It was suggested that AV was seen more often in BD than in normal population. AV is a common and very frequent skin lesion. The lesions are polymorphic, and are noninflamed (closed or open comedones) or inflamed (papules, pustules, nodules). Objectives: To find if ...
Classification of muco-cutaneous lesions of Behcet's Disease.
Abstract: Introduction: The diagnosis of Behcet's Disease (BD) is based on clinical criteria. Muco-cutaneous symptoms are the most important among them. Materials and Methods: From 1992 to 1999 we screened systematically all patients attending the Behcet's Disease Research Unit for muco cutaneous lesions. Only recurrent lesions were taken in consideration. Results: Mucous-membrane lesions: 1- Oral aphthosis was seen in 96.1%+ 0.6 of patients. The separation in major and minor aphthosis has no interest. ...
Long-term outcome of ocular manifestations in Behcet's Disease.
Abstract: Introduction: The natural history of ocular manifestations is very poor in Behcet's Disease (BD). The lesions progress by successive attacks leading to sever loss of vision or blindness. Aggressive treatments, by the association of cytotoxic drugs and steroids, have dramatically changed the outcome. However, still some ophthalmologists are convinced that the improvement is temporary and in the long run the eyes progress toward blindness. The aim of this study was ...
Mid-term Results of Azathiopriae to Ocular Lesions of Behcet's Disease.
Abstract: lntroduction: Ocular lesions of Behcet's Disease (BD) need aggressive treatment to prevent from severe loss of vision or blindness. Cytotoxic drugs are necessary for the treatment. A short-term study with azathioprine (AZA) was presented to the 8th lnternational Conference on Behcet's Disease. The aim of this study is to present the results for a longer period of time. Materials & methods: Patients (32) who received more than 9 months of treatment ...
Azathioprine for The Treatment of Ophthalmological Lesions of Behcet’s Disease.
Abstract: Introduction: Posterior uveitis (PU) and retinal vasculitis (RV) are the main morbidity factor in Behcet’s Disease (BD). They usually progress toward severe loss of vision or blindness. They need aggressive treatment with cytotoxic drugs. Azathioprine was demonstrated, in a double blind control study, to be effective in Behcet’s Disease. The aim of this study was to evaluate the efficacy of Azathioprine in ocular lesions of BD, and to compare ...
Epidemiology of Behcet's disease in Iran.
Abstract: Introduction: The geographical distribution of Behcet's Disease (B.D) is thought to be due to the predisposing factor(s) spread along the Silk Route. It is widely accepted that the predisposing factor(s) is of genetic origin. However the rarity of BD among Hawaiian's Japanese immigrants may be in favor of environmental factors. Iran is situated in the middle of the Silk Route. Caucasians account for 75.4%, Turks (from Mongoloid ethnic origin) for ...
Familial Oral Aphthosis in General Population As Compared To Behcet’s Disease.
Abstract: Introduction: Oral aphthosis (OA) is seen in 96% of patient with Behcet’s Disease (BB) OA is said to be rather frequent in the general population. It was therefore interesting to determine whether OA in the general population had also a genetic background as it is for BD. It was also interesting to determine if the genetic background was similar in both conditions (BD and OA in the general population). Therefore, ...